FIDELITY OF HUMAN OVARIAN CANCER PATIENT-DERIVED XENOGRAFTS IN A PARTIALLY HUMANIZED MOUSE MODEL FOR PRECLINICAL TESTING OF IMMUNOTHERAPIES

Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies

Background Immune checkpoint blockers (ICBs) have been approved by the Food and end table Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers.Since ICB only works in a subset of patients and has limited efficacy in treating ovarian cancer (OVC), developing preclinical model

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Using Fuzzy Logic Algorithms and Growing Hierarchical Self-Organizing Maps to Define Efficient Security Inspection Strategies in a Container Terminal

Maritime transport is one of the oldest methods of moving various types of goods, and it continues to have an important role in our modern society.More than 20 million containers are transported across the oceans daily.However, this form of transportation is constantly threatened by illegal operations, such as the smuggling of goods or people and m

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